Bush, William S., PhD

Will Bush_crop

William S. Bush, PhD

Assistant Professor

wsb36@case.edu | 216.368.5658 | Wolstein Research Bldg. 2530

Education

Ph.D., 2008, Vanderbilt University
M.S., 2008, Vanderbilt University

Recent Publications

  1. McKay, JD, Hung, RJ, Han, Y, Zong, X, Carreras-Torres, R, Christiani, DC, Caporaso, NE, Johansson, M, Xiao, X, Li, Y, Byun, J, Dunning, A, Pooley, KA, Qian, DC, Ji, X, Liu, G, Timofeeva, MN, Bojesen, SE, Wu, X, Le Marchand, L, Albanes, D, Bickeböller, H, Aldrich, MC, Bush, WS, Tardon, A, Rennert, G, Teare, MD, Field, JK, Kiemeney, LA, Lazarus, P, Haugen, A, Lam, S, Schabath, MB, Andrew, AS, Shen, H, Hong, YC, Yuan, JM, Bertazzi, PA, Pesatori, AC, Ye, Y, Diao, N, Su, L, Zhang, R, Brhane, Y, Leighl, N, Johansen, JS, Mellemgaard, A, Saliba, W, Haiman, CA, Wilkens, LR, Fernandez-Somoano, A, Fernandez-Tardon, G, van der Heijden, HFM, Kim, JH, Dai, J, Hu, Z, Davies, MPA, Marcus, MW, Brunnström, H, Manjer, J, Melander, O, Muller, DC, Overvad, K, Trichopoulou, A, Tumino, R, Doherty, JA, Barnett, MP, Chen, C, Goodman, GE, Cox, A, Taylor, F, Woll, P, Brüske, I, Wichmann, HE, Manz, J, Muley, TR, Risch, A, Rosenberger, A, Grankvist, K, Johansson, M, Shepherd, FA, Tsao, MS, Arnold, SM, Haura, EB, Bolca, C, Holcatova, I, Janout, V, Kontic, M, Lissowska, J, Mukeria, A, Ognjanovic, S, Orlowski, TM, Scelo, G, Swiatkowska, B, Zaridze, D, Bakke, P, Skaug, V, Zienolddiny, S, Duell, EJ, Butler, LM, Koh, WP, Gao, YT, Houlston, RS, McLaughlin, J, Stevens, VL, Joubert, P, Lamontagne, M, Nickle, DC, Obeidat, M, Timens, W, Zhu, B, Song, L, Kachuri, L, Artigas, MS, Tobin, MD, Wain, LV, SpiroMeta Consortium, Rafnar, T, Thorgeirsson, TE, Reginsson, GW, Stefansson, K, Hancock, DB, Bierut, LJ, Spitz, MR, Gaddis, NC, Lutz, SM, Gu, F, Johnson, EO, Kamal, A, Pikielny, C, Zhu, D, Lindströem, S, Jiang, X, Tyndale, RF, Chenevix-Trench, G, Beesley, J, Bossé, Y, Chanock, S, Brennan, P, Landi, MT, Amos, CI. Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes. Nat. Genet. 2017; 49 (7): 1126-1132. PubMed PMID:28604730 PubMed Central PMC5510465.
  2. Jia, P, Zhao, Z, Hulgan, T, Bush, WS, Samuels, DC, Bloss, CS, Heaton, RK, Ellis, RJ, Schork, N, Marra, CM, Collier, AC, Clifford, DB, Gelman, BB, Sacktor, N, Morgello, S, Simpson, DM, McCutchan, JA, Barnholtz-Sloan, JS, Franklin, DR, Rosario, D, Letendre, SL, Grant, I, Kallianpur, AR, CHARTER Study Group. Genome-wide association study of HIV-associated neurocognitive disorder (HAND): A CHARTER group study. Am. J. Med. Genet. B Neuropsychiatr. Genet. 2017; 174 (4): 413-426. PubMed PMID:28447399 PubMed Central PMC5435520.
  3. Patton, SM, Wang, Q, Hulgan, T, Connor, JR, Jia, P, Zhao, Z, Letendre, SL, Ellis, RJ, Bush, WS, Samuels, DC, Franklin, DR, Kaur, H, Iudicello, J, Grant, I, Kallianpur, AR. Cerebrospinal fluid (CSF) biomarkers of iron status are associated with CSF viral load, antiretroviral therapy, and demographic factors in HIV-infected adults. Fluids Barriers CNS 2017; 14 (1): 11. PubMed PMID:28427421 PubMed Central PMC5399327.
  4. Zubair, N, Graff, M, Luis Ambite, J, Bush, WS, Kichaev, G, Lu, Y, Manichaikul, A, Sheu, WH, Absher, D, Assimes, TL, Bielinski, SJ, Bottinger, EP, Buzkova, P, Chuang, LM, Chung, RH, Cochran, B, Dumitrescu, L, Gottesman, O, Haessler, JW, Haiman, C, Heiss, G, Hsiung, CA, Hung, YJ, Hwu, CM, Juang, JJ, Le Marchand, L, Lee, IT, Lee, WJ, Lin, LA, Lin, D, Lin, SY, Mackey, RH, Martin, LW, Pasaniuc, B, Peters, U, Predazzi, I, Quertermous, T, Reiner, AP, Robinson, J, Rotter, JI, Ryckman, KK, Schreiner, PJ, Stahl, E, Tao, R, Tsai, MY, Waite, LL, Wang, TD, Buyske, S, Ida Chen, YD, Cheng, I, Crawford, DC, Loos, RJF, Rich, SS, Fornage, M, North, KE, Kooperberg, C, Carty, CL. Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci. Hum. Mol. Genet. 2016; 25 (24): 5500-5512. PubMed PMID:28426890 .
  5. Fernández-Rhodes, L, Gong, J, Haessler, J, Franceschini, N, Graff, M, Nishimura, KK, Wang, Y, Highland, HM, Yoneyama, S, Bush, WS, Goodloe, R, Ritchie, MD, Crawford, D, Gross, M, Fornage, M, Buzkova, P, Tao, R, Isasi, C, Avilés-Santa, L, Daviglus, M, Mackey, RH, Houston, D, Gu, CC, Ehret, G, Nguyen, KH, Lewis, CE, Leppert, M, Irvin, MR, Lim, U, Haiman, CA, Le Marchand, L, Schumacher, F, Wilkens, L, Lu, Y, Bottinger, EP, Loos, RJL, Sheu, WH, Guo, X, Lee, WJ, Hai, Y, Hung, YJ, Absher, D, Wu, IC, Taylor, KD, Lee, IT, Liu, Y, Wang, TD, Quertermous, T, Juang, JJ, Rotter, JI, Assimes, T, Hsiung, CA, Chen, YI, Prentice, R, Kuller, LH, Manson, JE, Kooperberg, C, Smokowski, P, Robinson, WR, Gordon-Larsen, P, Li, R, Hindorff, L, Buyske, S, Matise, TC, Peters, U, North, KE. Trans-ethnic fine-mapping of genetic loci for body mass index in the diverse ancestral populations of the Population Architecture using Genomics and Epidemiology (PAGE) Study reveals evidence for multiple signals at established loci. Hum. Genet. 2017; 136 (6): 771-800. PubMed PMID:28391526 PubMed Central PMC5485655.
  6. Samuels, DC, Kallianpur, AR, Ellis, RJ, Bush, WS, Letendre, S, Franklin, D, Grant, I, Hulgan, T. European Mitochondrial DNA Haplogroups are Associated with Cerebrospinal Fluid Biomarkers of Inflammation in HIV Infection. Pathog Immun ; 1 (2): 330-351. PubMed PMID:28317034 PubMed Central PMC5351881.
  7. Butkiewicz, M, Haines, JL, Bush, WS. Introducing COCOS: codon consequence scanner for annotating reading frame changes induced by stop-lost and frame shift variants. Bioinformatics 2017; 33 (10): 1561-1562. PubMed PMID:28122779 PubMed Central PMC5423451.
  8. Bush, WS, Crawford, DC. Predicting Incident Coronary Heart Disease Many Markers at a Time. Circ Cardiovasc Genet 2016; 9 (6): 472-473. PubMed PMID:27998944 .
  9. Hall, JB, Bush, WS. Analysis of Heritability Using Genome-Wide Data. Curr Protoc Hum Genet 2016; 91 : 1.30.1-1.30.10. PubMed PMID:27727439 PubMed Central PMC5127448.
  10. Fish, AE, Capra, JA, Bush, WS. Are Interactions between cis-Regulatory Variants Evidence for Biological Epistasis or Statistical Artifacts? Am. J. Hum. Genet. 2016; 99 (4): 817-830. PubMed PMID:27640306 PubMed Central PMC5065654.
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