Dana Crawford_crop

Dana C. Crawford, PhD

Associate Professor

dcc64@case.edu | 216.368.5546  | Wolstein Research Building Rm. 2527

Education

Ph.D., 2000, Emory University.

Research Interests

Genetic architecture of complex traits in diverse populations drawn from epidemiologic and clinical (electronic health records) settings.

Recent Publications

  1. Zubair, N, Graff, M, Luis Ambite, J, Bush, WS, Kichaev, G, Lu, Y, Manichaikul, A, Sheu, WH, Absher, D, Assimes, TL, Bielinski, SJ, Bottinger, EP, Buzkova, P, Chuang, LM, Chung, RH, Cochran, B, Dumitrescu, L, Gottesman, O, Haessler, JW, Haiman, C, Heiss, G, Hsiung, CA, Hung, YJ, Hwu, CM, Juang, JJ, Le Marchand, L, Lee, IT, Lee, WJ, Lin, LA, Lin, D, Lin, SY, Mackey, RH, Martin, LW, Pasaniuc, B, Peters, U, Predazzi, I, Quertermous, T, Reiner, AP, Robinson, J, Rotter, JI, Ryckman, KK, Schreiner, PJ, Stahl, E, Tao, R, Tsai, MY, Waite, LL, Wang, TD, Buyske, S, Ida Chen, YD, Cheng, I, Crawford, DC, Loos, RJF, Rich, SS, Fornage, M, North, KE, Kooperberg, C, Carty, CL. Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci. Hum. Mol. Genet. 2016; 25 (24): 5500-5512. PubMed PMID:28426890 .
  2. Fernández-Rhodes, L, Gong, J, Haessler, J, Franceschini, N, Graff, M, Nishimura, KK, Wang, Y, Highland, HM, Yoneyama, S, Bush, WS, Goodloe, R, Ritchie, MD, Crawford, D, Gross, M, Fornage, M, Buzkova, P, Tao, R, Isasi, C, Avilés-Santa, L, Daviglus, M, Mackey, RH, Houston, D, Gu, CC, Ehret, G, Nguyen, KH, Lewis, CE, Leppert, M, Irvin, MR, Lim, U, Haiman, CA, Le Marchand, L, Schumacher, F, Wilkens, L, Lu, Y, Bottinger, EP, Loos, RJL, Sheu, WH, Guo, X, Lee, WJ, Hai, Y, Hung, YJ, Absher, D, Wu, IC, Taylor, KD, Lee, IT, Liu, Y, Wang, TD, Quertermous, T, Juang, JJ, Rotter, JI, Assimes, T, Hsiung, CA, Chen, YI, Prentice, R, Kuller, LH, Manson, JE, Kooperberg, C, Smokowski, P, Robinson, WR, Gordon-Larsen, P, Li, R, Hindorff, L, Buyske, S, Matise, TC, Peters, U, North, KE. Trans-ethnic fine-mapping of genetic loci for body mass index in the diverse ancestral populations of the Population Architecture using Genomics and Epidemiology (PAGE) Study reveals evidence for multiple signals at established loci. Hum. Genet. 2017; 136 (6): 771-800. PubMed PMID:28391526 PubMed Central PMC5485655.
  3. Dumitrescu, L, Ritchie, MD, Denny, JC, El Rouby, NM, McDonough, CW, Bradford, Y, Ramirez, AH, Bielinski, SJ, Basford, MA, Chai, HS, Peissig, P, Carrell, D, Pathak, J, Rasmussen, LV, Wang, X, Pacheco, JA, Kho, AN, Hayes, MG, Matsumoto, M, Smith, ME, Li, R, Cooper-DeHoff, RM, Kullo, IJ, Chute, CG, Chisholm, RL, Jarvik, GP, Larson, EB, Carey, D, McCarty, CA, Williams, MS, Roden, DM, Bottinger, E, Johnson, JA, de Andrade, M, Crawford, DC. Genome-wide study of resistant hypertension identified from electronic health records. PLoS ONE 2017; 12 (2): e0171745. PubMed PMID:28222112 PubMed Central PMC5319785.
  4. Bush, WS, Crawford, DC. Predicting Incident Coronary Heart Disease Many Markers at a Time. Circ Cardiovasc Genet 2016; 9 (6): 472-473. PubMed PMID:27998944 .
  5. Avery, CL, Wassel, CL, Richard, MA, Highland, HM, Bien, S, Zubair, N, Soliman, EZ, Fornage, M, Bielinski, SJ, Tao, R, Seyerle, AA, Shah, SJ, Lloyd-Jones, DM, Buyske, S, Rotter, JI, Post, WS, Rich, SS, Hindorff, LA, Jeff, JM, Shohet, RV, Sotoodehnia, N, Lin, DY, Whitsel, EA, Peters, U, Haiman, CA, Crawford, DC, Kooperberg, C, North, KE. Fine mapping of QT interval regions in global populations refines previously identified QT interval loci and identifies signals unique to African and Hispanic descent populations. Heart Rhythm 2017; 14 (4): 572-580. PubMed PMID:27988371 PubMed Central PMC5448160.
  6. Restrepo, NA, Butkiewicz, M, McGrath, JA, Crawford, DC. Shared Genetic Etiology of Autoimmune Diseases in Patients from a Biorepository Linked to De-identified Electronic Health Records. Front Genet 2016; 7 : 185. PubMed PMID:27812365 PubMed Central PMC5071319.
  7. Restrepo, NA, Farber-Eger, E, Crawford, DC. Searching in the Dark: Phenotyping Diabetic Retinopathy in a De-Identified Electronic Medical Record Sample of African Americans. AMIA Jt Summits Transl Sci Proc 2016; 2016 : 221-30. PubMed PMID:27570675 PubMed Central PMC5001772.
  8. Butkiewicz, M, Restrepo, NA, Haines, JL, Crawford, DC. DRUG-DRUG INTERACTION PROFILES OF MEDICATION REGIMENS EXTRACTED FROM A DE-IDENTIFIED ELECTRONIC MEDICAL RECORDS SYSTEM. AMIA Jt Summits Transl Sci Proc 2016; 2016 : 33-40. PubMed PMID:27570646 PubMed Central PMC5001747.
  9. Verma, A, Verma, SS, Pendergrass, SA, Crawford, DC, Crosslin, DR, Kuivaniemi, H, Bush, WS, Bradford, Y, Kullo, I, Bielinski, SJ, Li, R, Denny, JC, Peissig, P, Hebbring, S, De Andrade, M, Ritchie, MD, Tromp, G. eMERGE Phenome-Wide Association Study (PheWAS) identifies clinical associations and pleiotropy for stop-gain variants. BMC Med Genomics 2016; 9 Suppl 1 : 32. PubMed PMID:27535653 PubMed Central PMC4989894.
  10. van 't Hof, FN, Ruigrok, YM, Lee, CH, Ripke, S, Anderson, G, de Andrade, M, Baas, AF, Blankensteijn, JD, Böttinger, EP, Bown, MJ, Broderick, J, Bijlenga, P, Carrell, DS, Crawford, DC, Crosslin, DR, Ebeling, C, Eriksson, JG, Fornage, M, Foroud, T, von Und Zu Fraunberg, M, Friedrich, CM, Gaál, EI, Gottesman, O, Guo, DC, Harrison, SC, Hernesniemi, J, Hofman, A, Inoue, I, Jääskeläinen, JE, Jones, GT, Kiemeney, LA, Kivisaari, R, Ko, N, Koskinen, S, Kubo, M, Kullo, IJ, Kuivaniemi, H, Kurki, MI, Laakso, A, Lai, D, Leal, SM, Lehto, H, LeMaire, SA, Low, SK, Malinowski, J, McCarty, CA, Milewicz, DM, Mosley, TH, Nakamura, Y, Nakaoka, H, Niemelä, M, Pacheco, J, Peissig, PL, Pera, J, Rasmussen-Torvik, L, Ritchie, MD, Rivadeneira, F, van Rij, AM, Santos-Cortez, RL, Saratzis, A, Slowik, A, Takahashi, A, Tromp, G, Uitterlinden, AG, Verma, SS, Vermeulen, SH, Wang, GT, Aneurysm Consortium; Vascular Research Consortium of New Zealand, Han, B, Rinkel, GJ, de Bakker, PI. Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms. J Am Heart Assoc 2016; 5 (7): . PubMed PMID:27418160 PubMed Central PMC5015357.
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