Farren BS Briggs_crop

Farren B.S. Briggs, PhD, ScM

Assistant Professor

farren.briggs@case.edu | 216.368.5636 | Wolstein Research Bldg. 1312

 

Education

Ph.D., 2010, Epidemiology, University of California, Berkeley
Sc.M., 2005, Biostatistics, Brown University

Research Interests

Integrating genomic, epigenetic, and environmental data to characterize multiple sclerosis, and other autoimmune and neurodegenerative diseases, susceptibility and progression.
Developing strategies for investigating multiplex gene(n)-gene and gene(n)-environment relationships in complex diseases.
Utilizing bioinformatics tools for extracting information from genetic and epigenetic data.
Using genetic and epigenetic profiles to classify patients with complex diseases into homogenous subsets for analysis.
Identifying genetic and environmental factors associated with conversion to MS from clinically isolated syndrome.
Quantifying disability and identifying symptomatology trajectories in MS patients.
Identifying genetic and modifiable risk factors contributing to MS progression.
Characterizing the molecular phenotype of mesenchymal stem cells in MS patients.

Professional Memberships

American Society of Human Genetics
Society for Epidemiologic Research

Recent Publications

  1. Galarza-Muñoz, G, Briggs, FB, Evsyukova, I, Schott-Lerner, G, Kennedy, EM, Nyanhete, T, Wang, L, Bergamaschi, L, Widen, SG, Tomaras, GD, Ko, DC, Bradrick, SS, Barcellos, LF, Gregory, SG, Garcia-Blanco, MA. Human Epistatic Interaction Controls IL7R Splicing and Increases Multiple Sclerosis Risk. Cell 2017; 169 (1): 72-84.e13. PubMed PMID:28340352 PubMed Central PMC5456452.
  2. Taqui, A, Cerejo, R, Itrat, A, Briggs, FB, Reimer, AP, Winners, S, Organek, N, Buletko, AB, Sheikhi, L, Cho, SM, Buttrick, M, Donohue, MM, Khawaja, Z, Wisco, D, Frontera, JA, Russman, AN, Hustey, FM, Kralovic, DM, Rasmussen, P, Uchino, K, Hussain, MS, Cleveland Pre-Hospital Acute Stroke Treatment (PHAST) Group. Reduction in time to treatment in prehospital telemedicine evaluation and thrombolysis. Neurology 2017; 88 (14): 1305-1312. PubMed PMID:28275084 .
  3. Briggs, FB, Gunzler, DD, Ontaneda, D, Marrie, RA. Smokers with MS have greater decrements in quality of life and disability than non-smokers. Mult. Scler. 2017; : 1352458516685169. PubMed PMID:28059618 PubMed Central PMC5494015.
  4. Gunzler, DD, Morris, N, Perzynski, A, Ontaneda, D, Briggs, F, Miller, D, Bermel, RA. Heterogeneous depression trajectories in multiple sclerosis patients. Mult Scler Relat Disord 2016; 9 : 163-9. PubMed PMID:27645367 PubMed Central PMC5031243.
  5. Hsu, LI, Briggs, F, Shao, X, Metayer, C, Wiemels, JL, Chokkalingam, AP, Barcellos, LF. Pathway Analysis of Genome-wide Association Study in Childhood Leukemia among Hispanics. Cancer Epidemiol. Biomarkers Prev. 2016; 25 (5): 815-22. PubMed PMID:26941364 PubMed Central PMC4873450.
  6. George, MF, Holingue, CB, Briggs, FB, Shao, X, Bellesis, KH, Whitmer, RA, Schaefer, C, Benedict, RH, Barcellos, LF. Feasibility study for remote assessment of cognitive function in multiple sclerosis. J Neurol Neuromedicine 2016; 1 (8): 10-18. PubMed PMID:28255581 PubMed Central PMC5330281.
  7. Itrat, A, Taqui, A, Cerejo, R, Briggs, F, Cho, SM, Organek, N, Reimer, AP, Winners, S, Rasmussen, P, Hussain, MS, Uchino, K, Cleveland Pre-Hospital Acute Stroke Treatment Group. Telemedicine in Prehospital Stroke Evaluation and Thrombolysis: Taking Stroke Treatment to the Doorstep. JAMA Neurol 2016; 73 (2): 162-8. PubMed PMID:26641366 .
  8. Briggs, FB, Green, MC, Ritterman Weintraub, ML. Role of socioeconomic position in multiple sclerosis etiology. Neurodegener Dis Manag 2015; 5 (4): 333-43. PubMed PMID:26295724 .
  9. Cerejo, R, John, S, Buletko, AB, Taqui, A, Itrat, A, Organek, N, Cho, SM, Sheikhi, L, Uchino, K, Briggs, F, Reimer, AP, Winners, S, Toth, G, Rasmussen, P, Hussain, MS. A Mobile Stroke Treatment Unit for Field Triage of Patients for Intraarterial Revascularization Therapy. J Neuroimaging ; 25 (6): 940-5. PubMed PMID:26179631 .
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