ENIGMA Journal Club

ENIGMA is our informal journal club for discussions of research in genetic epidemiology.  Organized by Dr. Fred Schumacher, the genesis of such a tortured acronym is an enigma in and of itself (though the enigma machine is a great metaphor).  Each Wednesday at 4:00 PM we get together to have snacks and chat about a recent human genetics paper.  Some of our recent discussions are listed below!    

The promise of discovering population-specific disease-associated genes in South Asia

On October 4th, 2017 Kevin Chesmore presented “The promise of discovering population-specific disease-associated genes in South Asia”, a paper which provides an overview of potential genetic studies that could be conducted primarily in India.  We had a vigorous discussion on the motivations for this perspective piece, and touched on the idea of “genetic colonialism” and […]

Identification of individuals by trait prediction using whole-genome sequencing data

After a two week break for various meetings, we met on October 25th, 2017 to discuss “Identification of individuals by trait prediction using whole-genome sequencing data”.  We had a great discussion on the results of this paper and the potential impact this could have to study participation rates and data availability.  We also discussed the […]