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case western reserve university

DEPT. OF EPIDEMIOLOGY
& BIOSTATISTICS
 

SARA M. DEBANNE, PH.D.

Acting Director
Division of Biostatistics
Profesor Plenario (adjunct appointment) Departamento de Investigación, Universidad de Belgrano. Buenos Aires, Argentina.
Statistical modeling
Spread of tuberculosis in the community
Alzheimer's disease

Office: School of Medicine, Wood Bldg. WG-51
Phone: (216) 368-3895
E-mail: smd3@case.edu
Education
Lic. 1969, Universidad de Buenos Aires
Ph.D. 1977, M.S. 1974, Case Western Reserve University


Research Interests
Statistical modeling; spread of tuberculosis in the community; Alzheimer's disease.


Courses Taught
EPBI 431: Statistical Methods in Biological and Medical Sciences I
EPBI 492: Epidemiology: Statistical Methods
EPBI 499: Special Topics: Mathematical Modeling of Disease Progression


Professional Services
Study Section:
Physiological Sciences Study Section, Center for Scientific Review, National Institutes of Health. (ad-hoc, 1995)
Health Services Research Study Section, Center for Scientific Review, National Institutes of Health. (ad-hoc, 1994)
Epidemiology and Disease Control - subcommittee 1 Study Section, Center for Scientific Review, National Institutes of Health. (ad-hoc 1993, permanent member 1994-98, ad-hoc 1999-2000, permanent member 2001-2004).

Advisory Groups:
Adviser to the Technical Advisory Group on Strategic Planning for Poliomyelitis Eradication of the World Health Organization. (1999)
Expert witness for the U. S. Government's Occupational Safety and Health Administration (OSHA) on the proposed rule for occupational exposure to tuberculosis. (1998)

Editorial Boards:
Editor for Biostatistics. Gastrointestinal Endoscopy. (Official Journal of the American Society for Gastrointestinal Endoscopy)


Honors and Awards
American Statistical Association / National Science Foundation Senior Research Fellow at the National Center for Education Statistics of the U.S. Department of Education, Washington, D.C. (1998-1999)


Research Activities
Invitational Workshops
Eradication of Poliomyelitis in Europe. Technical Advisory Group on Strategic Planning for Poliomyelitis Eradication of the World Health Organization, Paris, France; June 1999. (Invited presentation)
Mathematical Modeling of Tuberculosis II. Robert Wood Johnson Foundation, San Francisco, California; April 1996. (Invited presentation)
Mathematical Modeling of Tuberculosis I. Robert Wood Johnson Foundation, San Francisco, California; February 1995. (Invited presentation)
Conference to Reestablish Control of Tuberculosis in the United States. American Lung Association, Washington DC; March 1994. (Invited presentation)
Learning from the Past: Defining the Future of Tuberculosis. Mathematical Modeling of Tuberculosis. Robert Wood Johnson Foundation, Atlanta, Georgia; November 1993.
Eradication of Poliomyelitis in the Americas. Technical Advisory Group of the Expanded Program on Immunization of the Pan American Health Organization, Washington, DC; January 1993. (Invited presentation)


Recent Publications (by area of application)
Tuberculosis

Bielefeld, RA, Debanne SM, Rowland DY. Storing sparse and repeated data in multivariate Markovian models of tuberculosis spread. Computers and Biomedical Research 1996;29:85-92.

Nolan C, Reichman L, Brenner E, Castro K, Cauthen G, Debanne SM, Fujiwara P, Hadler J, Hopewell P, Small P. The American Lung Association Conference on Reestablishing Control of Tuberculosis in the United States: Epidemiology. Am J Respir Crit Care Med 1996;154:251-262.

Daniel TM, Debanne SM. Estimation of the Annual Risk of Tuberculosis Infection for White Men in the United States. J Infec Dis 1997;175:1535-1537.

Rodriguez CG, Jankilevich SS, Capurro AF, Debanne SM. Tuberculosis in HIV-Infected Individuals: its Relationship with the Degree of Immunodefficiency. Investigación y Desarrollo Ambiental 1997:1-10.

Jankilevich SS, Debanne SM, Pilheu JA. Análisis de la Distribución del Tamaño de la Reacción al Test Tuberculínico Producido por Dos reactivos (PPD) de Diferente Procedencia. Estudio en una Muestra Poblacional del Area Metropolitana de Buenos Aires. Rev Arg Torax 1999;59:11-17.

Debanne SM, Bielefeld RA, Cauthen G, Daniel TM, Rowland DY. A Multivariate Markov Chain Model of Tuberculosis: Forecasts for the United States. Emerging Infectious Diseases 2000;6(2):30-39. Abstract

Teixeira L, Perkins MD, Johnson JL, Keller RP, Palaci M, Dettoni VV, Rocha LMC, Debanne S, Talbot E, Dietze R. Infection and disease among household contacts of patients with multi-drug resistant tuberculosis. Bulletin of the Int J Tuberc Lung Dis 2001;5(4):1-8.


Poliomyelitis Eradication

Debanne SM, Rowland DY. Statistical Certification of Eradication of Poliomyelitis in the Americas. Mathematical Biosciences 1998;150:83-103. Abstract


Aging Research

Ford AB, Mefrouche Z, Friedland R, Debanne SM. Smoking and Cognitive Impairment: A Population-Based Study. J Am Geriatrics Soc 1996;44:905-909.

Friedland R, Smyth K, Rowland D, Esteban-Santillan C, Koss E, Cole R, Lerner A, Whitehouse P, Petot G, Debanne SM. Pre-morbid Activities are Reduced in Patients with Alzheimer's Disease as Compared to Age- and Sex-matched Controls: Results of a Case-Control Study. Alz Dis: Biol, Diag & Therapy 1997;4:34-37.

Picot S, Debanne SM, Namazi K, Wykle M. Religiosity and Perceived Rewards of Black and White Caregivers. The Gerontologist 1997; 37:89-101.

Debanne SM, Patterson MB, Dick R, Riedel TM, Schnell A, Rowland DY. Validation of a Telephone Cognitive Assessment Battery. J Am Geriatrics Soc 1997;45:1352-1359.

Lerner A, Koss E, Debanne SM, Rowland DY, Friedland R. Smoking and Oestrogen- replacement Therapy as Protective Factors for Alzheimer's Disease. The Lancet 1997; 349:403.

Debanne SM, Rowland DY, Friedland, R, Lerner A. Smoking and Alzheimer’s Disease. The Lancet 1997;350:295.

Friedland R, Farrer L, Cupples LA, Debanne SM et al. Smoking and the Risk of Alzheimer’s Disease. The Lancet 1998;352:819.

Picot SJ, Zauszniewski JA, Holston EC, Debanne SM. Mood and Blood Pressure Responses in Black Female Caregivers and Noncaregivers. Nursing Research 1999; 48:150-161.

Debanne SM, Riedel T, Cleves M, Rowland DY. Association Between Alzheimer's Disease and Smoking: The Case for Sibling Controls. July 2001, J Am Geriatrics Soc. Abstract

Debanne SM, Rowland DY, Riedel T, Cleves M. Association of Alzheimer's Disease and Smoking: The Case for Sibling Controls. J Am Geriatrics Soc 2000;48:800-806.

Friedland RP, Fritsch T, Smyth KA, Koss E, Lerner AJ, Chen CH, Petot GJ, Debanne SM. Patients with Alzheimer’s Disease Have Reduced Premorbid Activities Compared to Healthy Controls. Proc Nat Acad Sciences 2001;98(6):3440-3445.

Debanne SM, Petot G,Li J, Koss E,Lerner AJ, Riedel TM, Rowland DY, Smyth kA, Friedland RP. On the Use of Surrogate Responders for Controls in a Case-control Study of Alzheimer’s Disease. To appear July 2001, J Am Geriatrics Soc.


Statistical Education

Debanne SM. Planning and Analysis of Clinical Studies. The planning of clinical studies: Bias and precision. Gastrointestinal Endoscopy 2000; 52(6):821-22.

Debanne SM. The planning of clinical studies: A matter of choice. Gastrointestinal Endoscopy 2001; 53(1);144-45. s

Debanne SM. The planning of clinical studies: Experimental studies. Gastrointestinal Endoscopy 2001; 53(2):271-272.

Debanne SM. The planning of clinical studies: Random and not so random assignments. Gastrointestinal Endoscopy 2001;53(3):404-405.

Debanne SM, Rowland DY. The planning of clinical studies: Statistical power, Part I. Gastrointestinal Endoscopy 2001;53(4):701-702.

Debanne SM, Rowland DY. The planning of clinical studies: Statistical power, Part II. Gastrointestinal Endoscopy 2001;53(5):842-843.