Farren BS Briggs_crop

Farren B. S. Briggs, Ph.D., Sc.M.

Assistant Professor

farren.briggs@case.edu | 216.368.5636 | Wolstein Research Bldg. 1312


Lab Page: http://epbiwww.case.edu/ndge/

Recent Activities: http://epbiwww.case.edu/ndge-lab/


Ph.D., 2010, Epidemiology, University of California, Berkeley
Sc.M., 2005, Biostatistics, Brown University
B.A., 2001, Biology, College of the Holy Cross

Research Interests

Most of my academic training has focused on characterizing the influence of genetic and non-genetic (primarily modifiable exposures) factors on susceptibility and disease manifestation of multiple sclerosis (MS).

My current research spans understanding the etiology and pathology of MS from the micro- to the macro-level. For example, investigating whether a diagnostic signature for MS can be derived from readily available technologies (i.e. metabolomic assays), improving the phenotyping of the disease (which is critical for prognostication and  the development of novel therapeutics), and describing patterns in healthcare utilization.

I also conduct research in other neurological and autoimmune diseases, such as Parksinson’s Disease, stroke, neuromyelitis optica and tranverse myelitis.


I am the course director for PQHS 490 which introduces the fundamentals of Epidemiology. The class is aimed at graduate students, medical students, and advanced undergraduates. It is very much a 0-60mph class, where at the end of the semester students should be comfortable navigating most scientific articles, and able to discuss the study’s validity, the likely role of bias, and the causal implications.

Professional Memberships

American Society of Human Genetics

Society for Epidemiologic Research

Recent Publications

  1. Briggs, FBS, Wilson, BK, Pyatka, N, Colón-Zimmermann, K, Sajatovic, MM. Effects of a remotely delivered group-format epilepsy self-management program on adverse health outcomes in vulnerable people with epilepsy: A causal mediation analysis. Epilepsy Res. 2020; 162 : 106303. PubMed PMID:32151965 .
  2. Khalid, Z, Momotaz, H, Briggs, F, Cassidy, KA, Chaytor, NS, Fraser, RT, Janevic, MR, Jobst, B, Johnson, EK, Scal, P, Spruill, TM, Wilson, BK, Sajatovic, M. Depressive Symptoms in Older versus Younger People with Epilepsy: Findings from an Integrated Epilepsy Self-Management Clinical Research Dataset. J Multidiscip Healthc 2019; 12 : 981-988. PubMed PMID:31839708 PubMed Central PMC6904884.
  3. Briggs, F. Unraveling susceptibility to multiple sclerosis. Science 2019; 365 (6460): 1383-1384. PubMed PMID:31604260 .
  4. Briggs, FB, Hill, E. Estimating the prevalence of multiple sclerosis using 56.6 million electronic health records from the United States. Mult. Scler. 2019; : 1352458519864681. PubMed PMID:31339444 .
  5. Sheriff, MZ, Mansoor, E, Luther, J, Ananthakrishnan, AN, Abou Saleh, M, Ho, E, Briggs, FBS, Dave, M. Opportunistic Infections Are More Prevalent in Crohn's Disease and Ulcerative Colitis: A Large Population-Based Study. Inflamm. Bowel Dis. 2020; 26 (2): 291-300. PubMed PMID:31314891 .
  6. Crawford, DC, Cooke Bailey, JN, Briggs, FBS. Mind the gap: resources required to receive, process and interpret research-returned whole genome data. Hum. Genet. 2019; 138 (7): 691-701. PubMed PMID:31161416 PubMed Central PMC6767905.
  7. Gianfrancesco, MA, Briggs, FBS. Does early high body mass index influence onset of pediatric multiple sclerosis? Dev Med Child Neurol 2019; 61 (11): 1243. PubMed PMID:31044421 .
  8. Andersen, SL, Briggs, FBS, Winnike, JH, Natanzon, Y, Maichle, S, Knagge, KJ, Newby, LK, Gregory, SG. Metabolome-based signature of disease pathology in MS. Mult Scler Relat Disord 2019; 31 : 12-21. PubMed PMID:30877925 PubMed Central PMC6548586.
  9. Briggs, FBS, Thompson, NR, Conway, DS. Prognostic factors of disability in relapsing remitting multiple sclerosis. Mult Scler Relat Disord 2019; 30 : 9-16. PubMed PMID:30711764 .
  10. Hill, E, Abboud, H, Briggs, FBS. Prevalence of asthma in multiple sclerosis: A United States population-based study. Mult Scler Relat Disord 2019; 28 : 69-74. PubMed PMID:30557818 .
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