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- Education
- 2003, Ph.D., Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China. Dissertation: Transmission/disequilibrium test of candidate genes for Schizophrenia.
1998, B.Sc., Sichuan University, Chengdu, Sichuan, China
- Research Interests
- Genetic and molecular mechanisms that underlie serious mental illness with a primary focus on bipolar disorder; Meta-analysis; High-throughput DNA sequencing; Medical comorbidities; Pharmacogenomics.
- Professional Memberships
- American Society of Human Genetics
International Society of Psychiatric Genetics
- Select Publications
- Wang HY, Zhang FC, Gao JJ, Fan JB, Liu P, Zheng ZJ, Xi H, Sun Y, Gao XC, Huang TZ, Ke ZJ, Guo GR, Feng GY, Breen G, Clair DS, He L. Apolipoprotein E is a genetic risk factor for fetal iodine deficiency disorder in China. Molecular Psychiatry. 2000; 5(4): 363-368.
Fan JB*, Tang* JX, Gu NF, Feng GY, Zou FG, Xing YL, Shi JG, Zhao SM, Zhu SM, Ji LP, Sun WW, Zheng YL, Liu WQ, Breen G, St Clair D, He L. A family-based and case-control association study of the NOTCH4 gene and schizophrenia. Molecular Psychiatry. 2002; 7(1): 100-103. *Co-first authors.
Fan JB, Chen WY, Tang JX, Li S, Gu NF, Feng GY, Breen G, St Clair D, He L. Family-based association studies of COMT gene polymorphisms and schizophrenia in Chinese population. Molecular Psychiatry. 2002; 7(5): 446-447.
Tang JX, Zhou J, Fan JB, Li XW, Shi YY, Gu NF, Feng GY, Xing YL, Shi JG, He L. Family-based association study of DTNBP1 in 6p22.3 and schizophrenia. Molecular Psychiatry. 2003; 8(8): 717-8.
Fan JB, Zhang CS, Gu NF, Li XW, Sun WW, Wang HY, Feng GY, St Clair D, He L. Catechol-O-methyltransferase gene Val/Met functional polymorphism and risk of schizophrenia: A large-scale association study plus meta-analysis. Biological Psychiatry. 2005, 57(2): 139-144.
Fan JB, Sklar P. Meta-analysis reveals association between serotonin transporter gene STin2 VNTR polymorphism and schizophrenia. Molecular Psychiatry. 2005, 10(10) 928-938; 891.
Perlis RH, Purcell S, Fagerness J, Kirby A, Petryshen T, Fan JB, Sklar P. Family-based association study of lithium-related and other candidate genes in bipolar disorder. Archives of General Psychiatry. 2008 Jan; 65(1):53-61.
Fan JB, Sklar P. Genetics of bipolar disorder: Focus on brain-derived neurotrophic factor (BDNF) Val66Met polymorphism. Novartis Foundation Symposium 289: Growth Factors and Psychiatric Disorders. Novartis Foundation (Editor), Wiley, P60-73. 2008.
Sklar P, Smoller J, Fan J, Ferreira M, Chambert K, Nimgaonkar V, Devlin B, McQueen M, Laird N, Perlis R, DeBakker P, Thase M, Sachs G, Todd-Brown K, Kirby A, Gabriel S, Sougnez C, Gates C, Blumensteil B, Defelice M, Ardlie K, Franklin J, Blackwood people, McQuillin A, Bass N, Robinson M, Lawrence J, Anjorin A, Scolnick E, Daly M, Blackwood D, Gurling H, Purcell S. Whole-genome Association Study of Bipolar Disorder. Molecular Psychiatry. 2008 Jun; 13(6):558-569.
Ferreira MA, O'Donovan MC, Meng Y, Jones IR, Ruderfer DM, Jones L, Fan J, Kirov G, Perlis RH, Green EK, Smoller JW, Grozeva D, Stone J, Nikolov I, Chambert K, Hamshere ML, Nimgaonkar VL, Moskvina V, Thase ME, Caesar S, Sachs GS, Franklin J, Gordon-Smith K, Ardlie KG, Gabriel SB, Fraser C, Blumenstiel B, Defelice M, Breen G, Gill M, Morris DW, Elkin A, Muir WJ, McGhee KA, Williamson R, MacIntyre DJ, MacLean AW, St CD, Robinson M, Van Beck M, Pereira AC, Kandaswamy R, McQuillin A, Collier DA, Bass NJ, Young AH, Lawrence J, Ferrier IN, Anjorin A, Farmer A, Curtis D, Scolnick EM, McGuffin P, Daly MJ, Corvin AP, Holmans PA, Blackwood DH, Gurling HM, Owen MJ, Purcell SM, Sklar P, Craddock N; Wellcome Trust Case Control Consortium. Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nature Genetics. 2008 Sep; 40(9):1056-8.
Fan JB*, Ionita-Laza I*, McQueen MB, Devlin B, Purcell S, Faraone SV, Allen MH, Bowden CL, Calabrese JR, Fossey MD, Friedman ES, Gyulai L, Hauser P, Ketter TB, Marangell LB, Miklowitz DJ, Nierenberg AA, Patel JK, Sachs GS, Thase ME, Molay FB, Escamilla MA, Nimgaonkar VL, Sklar P, Laird NM, Smoller JW. Linkage Disequilibrium Mapping of the Chromosome 6q21-22.31 Bipolar I Disorder Susceptibility Locus. Am J Med Genet B Neuropsychiatr Genet. 2010 Jan 5;153B(1):29-37. *Co-first authors.
Petryshen TL, Sabeti PC, Aldinger KA, Fry B, Fan JB, Schaffner SF, Waggoner SG, Tahl AR, Sklar P. Population genetic study of the brain-derived neurotrophic factor (BDNF) gene. Molecular Psychiatry. 2010, In press.
- Additional Links
- Multidiscplinary Clinical Research Training Program (K12/KL2)
Last Updated (Tuesday, 05 October 2010 16:00)