jonathan_cropped

Jonathan L. Haines, PhD

Mary W. Sheldon MD Professor of Genomic Sciences, Chair

jonathan.haines@case.edu | 216.368.2478 | Wolstein Research Bldg., Rm 2528

Education

Recent Publications

  1. Iglesias, AI, Mishra, A, Vitart, V, Bykhovskaya, Y, Höhn, R, Springelkamp, H, Cuellar-Partida, G, Gharahkhani, P, Bailey, JNC, Willoughby, CE, Li, X, Yazar, S, Nag, A, Khawaja, AP, Polašek, O, Siscovick, D, Mitchell, P, Tham, YC, Haines, JL, Kearns, LS, Hayward, C, Shi, Y, van Leeuwen, EM, Taylor, KD, Blue Mountains Eye Study—GWAS group, Bonnemaijer, P, Rotter, JI, Martin, NG, Zeller, T, Mills, RA, Staffieri, SE, Jonas, JB, Schmidtmann, I, Boutin, T, Kang, JH, Lucas, SEM, Wong, TY, Beutel, ME, Wilson, JF, NEIGHBORHOOD Consortium, Wellcome Trust Case Control Consortium 2 (WTCCC2), Uitterlinden, AG, Vithana, EN, Foster, PJ, Hysi, PG, Hewitt, AW, Khor, CC, Pasquale, LR, Montgomery, GW, Klaver, CCW, Aung, T, Pfeiffer, N, Mackey, DA, Hammond, CJ, Cheng, CY, Craig, JE, Rabinowitz, YS, Wiggs, JL, Burdon, KP, van Duijn, CM, MacGregor, S. Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases. Nat Commun 2018; 9 (1): 1864. PubMed PMID:29760442 PubMed Central PMC5951816.
  2. Nittala, MG, Song, YE, Sardell, R, Adams, LD, Pan, S, Velaga, SB, Horst, V, Dana, D, Caywood, L, Laux, R, Fuzzell, D, Fuzzell, S, Scott, WK, Cooke Bailey, JN, Igo, RP Jr, Haines, J, Pericak-Vance, MA, Sadda, SR, Stambolian, D. AMISH EYE STUDY: Baseline Spectral Domain Optical Coherence Tomography Characteristics of Age-Related Macular Degeneration. Retina (Philadelphia, Pa.) 2018; : . PubMed PMID:29746403 .
  3. Hou, L, Kember, RL, Roach, JC, O'Connell, JR, Craig, DW, Bucan, M, Scott, WK, Pericak-Vance, M, Haines, JL, Crawford, MH, Shuldiner, AR, McMahon, FJ. Author Correction: A population-specific reference panel empowers genetic studies of Anabaptist populations. Sci Rep 2018; 8 (1): 6771. PubMed PMID:29691419 PubMed Central PMC5915589.
  4. Vardarajan, BN, Barral, S, Jaworski, J, Beecham, GW, Blue, E, Tosto, G, Reyes-Dumeyer, D, Medrano, M, Lantigua, R, Naj, A, Thornton, T, DeStefano, A, Martin, E, Wang, LS, Brown, L, Bush, W, van Duijn, C, Goate, A, Farrer, L, Haines, JL, Boerwinkle, E, Schellenberg, G, Wijsman, E, Pericak-Vance, MA, Mayeux, R, Alzheimer's Disease Sequencing Project, Wang, LS. Whole genome sequencing of Caribbean Hispanic families with late-onset Alzheimer's disease. Ann Clin Transl Neurol 2018; 5 (4): 406-417. PubMed PMID:29688227 PubMed Central PMC5899906.
  5. Lancour, D, Naj, A, Mayeux, R, Haines, JL, Pericak-Vance, MA, Schellenberg, GD, Crovella, M, Farrer, LA, Kasif, S. One for all and all for One: Improving replication of genetic studies through network diffusion. PLoS Genet. 2018; 14 (4): e1007306. PubMed PMID:29684019 PubMed Central PMC5933817.
  6. Butkiewicz, M, Blue, E, Leung, F, Jian, X, Marcora, E, Renton, A, Kuzma, A, Wang, LS, Koboldt, D, Haines, JL, Bush, WS. Functional Annotation of genomic variants in studies of Late-Onset Alzheimer's Disease. Bioinformatics 2018; : . PubMed PMID:29590295 .
  7. Blue, EE, Bis, JC, Dorschner, MO, Tsuang, DW, Barral, SM, Beecham, G, Below, JE, Bush, WS, Butkiewicz, M, Cruchaga, C, DeStefano, A, Farrer, LA, Goate, A, Haines, J, Jaworski, J, Jun, G, Kunkle, B, Kuzma, A, Lee, JJ, Lunetta, KL, Ma, Y, Martin, E, Naj, A, Nato, AQ, Navas, P, Nguyen, H, Reitz, C, Reyes, D, Salerno, W, Schellenberg, GD, Seshadri, S, Sohi, H, Thornton, TA, Valadares, O, van Duijn, C, Vardarajan, BN, Wang, LS, Boerwinkle, E, Dupuis, J, Pericak-Vance, MA, Mayeux, R, Wijsman, EM, on behalf of the Alzheimer’s Disease Sequencing Project. Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project. Dement Geriatr Cogn Disord 2018; 45 (1-2): 1-17. PubMed PMID:29486463 .
  8. Chung, J, Zhang, X, Allen, M, Wang, X, Ma, Y, Beecham, G, Montine, TJ, Younkin, SG, Dickson, DW, Golde, TE, Price, ND, Ertekin-Taner, N, Lunetta, KL, Mez, J, Alzheimer’s Disease Genetics Consortium, Mayeux, R, Haines, JL, Pericak-Vance, MA, Schellenberg, G, Jun, GR, Farrer, LA. Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer's disease. Alzheimers Res Ther 2018; 10 (1): 22. PubMed PMID:29458411 PubMed Central PMC5819208.
  9. Shiga, Y, Akiyama, M, Nishiguchi, KM, Sato, K, Shimozawa, N, Takahashi, A, Momozawa, Y, Hirata, M, Matsuda, K, Yamaji, T, Iwasaki, M, Tsugane, S, Oze, I, Mikami, H, Naito, M, Wakai, K, Yoshikawa, M, Miyake, M, Yamashiro, K, Japan Glaucoma Society Omics Group (JGS-OG), Kashiwagi, K, Iwata, T, Mabuchi, F, Takamoto, M, Ozaki, M, Kawase, K, Aihara, M, Araie, M, Yamamoto, T, Kiuchi, Y, Nakamura, M, Ikeda, Y, Sonoda, KH, Ishibashi, T, Nitta, K, Iwase, A, Shirato, S, Oka, Y, Satoh, M, Sasaki, M, Fuse, N, Suzuki, Y, Cheng, CY, Khor, CC, Baskaran, M, Perera, S, Aung, T, Vithana, EN, Cooke Bailey, JN, Kang, JH, Pasquale, LR, Haines, JL, NEIGHBORHOOD Consortium, Wiggs, JL, Burdon, KP, Gharahkhani, P, Hewitt, AW, Mackey, DA, MacGregor, S, Craig, JE, Allingham, RR, Hauser, M, Ashaye, A, Budenz, DL, Akafo, S, Williams, SEI, Kamatani, Y, Nakazawa, T, Kubo, M. Genome-wide association study identifies seven novel susceptibility loci for primary open-angle glaucoma. Hum. Mol. Genet. 2018; 27 (8): 1486-1496. PubMed PMID:29452408 .
  10. Gharahkhani, P, Burdon, KP, Cooke Bailey, JN, Hewitt, AW, Law, MH, Pasquale, LR, Kang, JH, Haines, JL, Souzeau, E, Zhou, T, Siggs, OM, Landers, J, Awadalla, M, Sharma, S, Mills, RA, Ridge, B, Lynn, D, Casson, R, Graham, SL, Goldberg, I, White, A, Healey, PR, Grigg, J, Lawlor, M, Mitchell, P, Ruddle, J, Coote, M, Walland, M, Best, S, Vincent, A, Gale, J, RadfordSmith, G, Whiteman, DC, Montgomery, GW, Martin, NG, Mackey, DA, Wiggs, JL, MacGregor, S, Craig, JE, NEIGHBORHOOD consortium. Analysis combining correlated glaucoma traits identifies five new risk loci for open-angle glaucoma. Sci Rep 2018; 8 (1): 3124. PubMed PMID:29449654 PubMed Central PMC5814451.
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