Jonathan L. Haines, PhD

Mary W. Sheldon MD Professor of Genomic Sciences and Chair | 216.368.2478 | Wolstein Research Bldg., Rm 2528



1979, BA               Colby College (Biology)

1984, PhD            University of Minnesota (Genetics & Cell Biology)

Dr. Haines is an internationally recognized researcher and educator with extensive experience in all aspects of genetic epidemiology, the study of the role of genes and the environment in human health and disease.

His research focus is big data analytics, with exper­tise in dis­or­ders of the eye and nervous system. Dr. Haines has located more than 20 causal and 200 asso­ci­ated genetic loci and has helped to define the genetic architecture of aging diseases, including macular degeneration and Alzheimer’s disease.

He emphasizes diversity in genetic sampling and a comprehensive view of data analytics. By applying sophisticated, com­pu­ta­tional meth­ods to large data sets, he seeks to discover contributing factors to diseases and chronic conditions, with an aim of improving patient care and community health.

Dr. Haines founded and directs the Cleveland Insti­tute for Com­pu­ta­tional Biol­ogy, a collaboration between Case Western Reserve University School of Medicine, University Hospitals Cleveland, and Cleveland Clinic. The Institute applies computational methods to large sets of patient data in order to improve the prevention, diagnosis, and treatment of disease.

Dr. Haines serves on a number of professional advisory councils including the National Institute of Health’s National Advisory Council for Human Genome Research, the scientific advisory panel for the NIH’s National Human Genome Research Institute Genome Sequencing Program, the board of directors for the National Organization for Rare Disorders, and the executive committee of the NIH’s Alzheimer’s Disease Sequencing Project. He serves on the editorial boards of Neurogenetics, Human Molecular Genetics, and Nature Genomic Medicine.

Before coming to Case Western Reserve University, Dr. Haines was at Harvard Medical School and was professor of molecular physiology and biophysics at Vanderbilt School of Medicine, with joint appointments in several departments. At Vanderbilt he was chief of the Division of Human Genomics and founding director of the Center for Human Genetics Research.

Recent Publications

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