We conduct research across a wide range of areas, integrating approaches to public and community health, biostatistics, epidemiology, and computational biology to address critical problems affecting human health. Some examples of our on-going research projects are highlighted below.
Dr. Satya Sahoo aims to characterize the role of brain connectivity in neurological disorders such as epilepsy using integrative graph models and highly scalable computational techniques. Brain connectivity measures are derived from multi-modal data, for example electrophysiological signal and diffusion MRI data, which are difficult to process, model, and analyze due to their volume, variety, […]
Dr. Daniel Tisch is an infectious diseases epidemiologist with 16 years experience studying methods to eliminate lymphatic filariasis. One billion people in the tropics and sub-tropics are at risk for lymphatic filariasis, a “Neglected Tropical Disease” (NTD) that causes elephantiasis, disfigurement of the male genitalia and painful swelling of the extremities. An ongoing global effort […]
For over two decades, Dr. Jonathan Haines has studied genetic factors that contribute to diseases of aging and “successful” aging in the Old Order Amish. A growing health concern in the US population is age-related macular degeneration (AMD), one of the leading causes of visual impairment and blindness in the elderly. It is well-established that genetic […]
Dr. Erika Trapl uses a classical epidemiological approach to study what is both a health and social issue: the use of cigars, cigarillos, and little cigars (CCLC) by adolescents and young adults. Using quantitative data from the Cleveland-Cuyahoga County Youth Risk Behavior Survey (YRBS) and qualitative data of from youth and young adults, she aims […]
Dr. Cathy Stein is a genetic epidemiologist who studies the molecular mechanisms that underly resistance to Mycobacterium tuberculosis. In collaboration with Drs. Scott Williams and Henry Boom, Dr. Stein is conducting a study in Uganda to examine individuals that are presumed resistant toM. tuberculosis infection, also called RSTRs. These individuals demonstrate persistently negative tuberculin skin tests and […]
The Prevention Research Center for Healthy Neighborhoods and the Center for Reducing Health Disparities are actively studying how changes in the neighborhood food environment affect the health of a community. Led by Drs. Darcy Freedman and Ashwini Sehgal, the FoodNEST project will examine changes in diet among people living in two targeted neighborhoods (one in […]