The Clinical & Translational Science Collaborative (CTSC) is the Cleveland-based part of a national consortium of research institutions working together to facilitate and transform scientific study relating to human health. With a shared goal of improved health, a broad scientific community - in the basic and behavioral sciences, in health advocacy, and in clinical practice - comes together with an engaged public community to leverage ideas and resources into results. This is a new model through which we are growing the research enterprise, developing practitioners and core competencies in the discipline of clinical and translational science, and putting research findings to use in clinical practice.
The CTSC encourages and enables collaborative participation in this research enterprise through communications, education, advocacy, clinical practice, shared ideas and resources, and pilot funding. Northeast Ohio researchers are seeing expedited success in their studies, and patients are benefiting, as a result. For more information about the Clinical & Translational Science Collaborative please visit http://casemed.case.edu/ctsc/.
Population-based databases (e.g., Medicare and Medicaid administrative databases, Vital Records, the Surveillance, Epidemiology, and End Results (SEER) data) represent rich sources of data, from “real world” settings, and offer an unparalleled opportunity to examine patterns of health care use, morbidity, mortality, and other process and outcomes measures in various subgroups of the population. In particular, where multiple treatment alternatives are available for a specific medical condition, these databases offer a unique opportunity to conduct comparative effectiveness research (CER) to identify the most effective treatment modality.
The Population Health and Outcomes Research Core (PHORC) integrates and mobilizes a vast archive of population-based databases and provides expertise in working with them to conduct outcomes and disparities research. This includes a large computing capacity to create an infrastructure to respond to researchers’ needs in comparative effectiveness research. This Laboratory serves researchers at CWRU, as well as the research community at large.