Scott M. Williams, PhD

Professor

smw154@case.edu | 216.368.5659 | Wood Bldg. WG-82A

Education

Ph.D. Washington University, St. Louis, 1981

Honors

2012 Fellow, American Association for the Advancement of Science

Professional Service

Section Editor, Natural Variation, PLoS Genetics, 2011-present
Section Editor, Genomics, Current Genetic Medicine Reports, 2012-present
Member Executive Committee, African Society of Human Genetics, 2013-present
Program Committee, Pacific Symposium on Biocomputing: Precision Medicine 2016

Recent Publications

  1. Amosco, MD, Tavera, GR, Villar, VAM, Naniong, JMA, David-Bustamante, LMG, Williams, SM, Jose, PA, Palmes-Saloma, CP. Non-additive effects of ACVR2A in preeclampsia in a Philippine population. BMC Pregnancy Childbirth 2019; 19 (1): 11. PubMed PMID:30621627 PubMed Central PMC6323705.
  2. Copenhaver, GP, Weir, B, Rothstein, M, Tang, H, Williams, SM, Barsh, GS. Doubling down on forensic twin studies. PLoS Genet. 2018; 14 (12): e1007831. PubMed PMID:30571773 PubMed Central PMC6301560.
  3. Sausville, LN, Williams, SM, Pozzi, A. Cytochrome P450 epoxygenases and cancer: A genetic and a molecular perspective. Pharmacol. Ther. 2018; : . PubMed PMID:30521883 .
  4. Williams, S, Hossain, M, Mishra, S, Gonzalez-Martinez, J, Najm, I, Ghosh, C. Expression and Functional Relevance of Death-Associated Protein Kinase in Human Drug-Resistant Epileptic Brain: Focusing on the Neurovascular Interface. Mol. Neurobiol. 2018; : . PubMed PMID:30414085 .
  5. Ligthart, S, Vaez, A, Võsa, U, Stathopoulou, MG, de Vries, PS, Prins, BP, Van der Most, PJ, Tanaka, T, Naderi, E, Rose, LM, Wu, Y, Karlsson, R, Barbalic, M, Lin, H, Pool, R, Zhu, G, Macé, A, Sidore, C, Trompet, S, Mangino, M, Sabater-Lleal, M, Kemp, JP, Abbasi, A, Kacprowski, T, Verweij, N, Smith, AV, Huang, T, Marzi, C, Feitosa, MF, Lohman, KK, Kleber, ME, Milaneschi, Y, Mueller, C, Huq, M, Vlachopoulou, E, Lyytikäinen, LP, Oldmeadow, C, Deelen, J, Perola, M, Zhao, JH, Feenstra, B, LifeLines Cohort Study, Amini, M, CHARGE Inflammation Working Group, Lahti, J, Schraut, KE, Fornage, M, Suktitipat, B, Chen, WM, Li, X, Nutile, T, Malerba, G, Luan, J, Bak, T, Schork, N, Del Greco M, F, Thiering, E, Mahajan, A, Marioni, RE, Mihailov, E, Eriksson, J, Ozel, AB, Zhang, W, Nethander, M, Cheng, YC, Aslibekyan, S, Ang, W, Gandin, I, Yengo, L, Portas, L, Kooperberg, C, Hofer, E, Rajan, KB, Schurmann, C, den Hollander, W, Ahluwalia, TS, Zhao, J, Draisma, HHM, Ford, I, Timpson, N, Teumer, A, Huang, H, Wahl, S, Liu, Y, Huang, J, Uh, HW, Geller, F, Joshi, PK, Yanek, LR, Trabetti, E, Lehne, B, Vozzi, D, Verbanck, M, Biino, G, Saba, Y, Meulenbelt, I, O'Connell, JR, Laakso, M, Giulianini, F, Magnusson, PKE, Ballantyne, CM, Hottenga, JJ, Montgomery, GW, Rivadineira, F, Rueedi, R, Steri, M, Herzig, KH, Stott, DJ, Menni, C, Frånberg, M, St Pourcain, B, Felix, SB, Pers, TH, Bakker, SJL, Kraft, P, Peters, A, Vaidya, D, Delgado, G, Smit, JH, Großmann, V, Sinisalo, J, Seppälä, I, Williams, SR, Holliday, EG, Moed, M, Langenberg, C, Räikkönen, K, Ding, J, Campbell, H, Sale, MM, Chen, YI, James, AL, Ruggiero, D, Soranzo, N, Hartman, CA, Smith, EN, Berenson, GS, Fuchsberger, C, Hernandez, D, Tiesler, CMT, Giedraitis, V, Liewald, D, Fischer, K, Mellström, D, Larsson, A, Wang, Y, Scott, WR, Lorentzon, M, Beilby, J, Ryan, KA, Pennell, CE, Vuckovic, D, Balkau, B, Concas, MP, Schmidt, R, Mendes de Leon, CF, Bottinger, EP, Kloppenburg, M, Paternoster, L, Boehnke, M, Musk, AW, Willemsen, G, Evans, DM, Madden, PAF, Kähönen, M, Kutalik, Z, Zoledziewska, M, Karhunen, V, Kritchevsky, SB, Sattar, N, Lachance, G, Clarke, R, Harris, TB, Raitakari, OT, Attia, JR, van Heemst, D, Kajantie, E, Sorice, R, Gambaro, G, Scott, RA, Hicks, AA, Ferrucci, L, Standl, M, Lindgren, CM, Starr, JM, Karlsson, M, Lind, L, Li, JZ, Chambers, JC, Mori, TA, de Geus, EJCN, Heath, AC, Martin, NG, Auvinen, J, Buckley, BM, de Craen, AJM, Waldenberger, M, Strauch, K, Meitinger, T, Scott, RJ, McEvoy, M, Beekman, M, Bombieri, C, Ridker, PM, Mohlke, KL, Pedersen, NL, Morrison, AC, Boomsma, DI, Whitfield, JB, Strachan, DP, Hofman, A, Vollenweider, P, Cucca, F, Jarvelin, MR, Jukema, JW, Spector, TD, Hamsten, A, Zeller, T, Uitterlinden, AG, Nauck, M, Gudnason, V, Qi, L, Grallert, H, Borecki, IB, Rotter, JI, März, W, Wild, PS, Lokki, ML, Boyle, M, Salomaa, V, Melbye, M, Eriksson, JG, Wilson, JF, Penninx, BWJH, Becker, DM, Worrall, BB, Gibson, G, Krauss, RM, Ciullo, M, Zaza, G, Wareham, NJ, Oldehinkel, AJ, Palmer, LJ, Murray, SS, Pramstaller, PP, Bandinelli, S, Heinrich, J, Ingelsson, E, Deary, IJ, Mägi, R, Vandenput, L, van der Harst, P, Desch, KC, Kooner, JS, Ohlsson, C, Hayward, C, Lehtimäki, T, Shuldiner, AR, Arnett, DK, Beilin, LJ, Robino, A, Froguel, P, Pirastu, M, Jess, T, Koenig, W, Loos, RJF, Evans, DA, Schmidt, H, Smith, GD, Slagboom, PE, Eiriksdottir, G, Morris, AP, Psaty, BM, Tracy, RP, Nolte, IM, Boerwinkle, E, Visvikis-Siest, S, Reiner, AP, Gross, M, Bis, JC, Franke, L, Franco, OH, Benjamin, EJ, Chasman, DI, Dupuis, J, Snieder, H, Dehghan, A, Alizadeh, BZ. Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders. Am. J. Hum. Genet. 2018; 103 (5): 691-706. PubMed PMID:30388399 PubMed Central PMC6218410.
  6. Kim, SP, Gross, CP, Shah, ND, Tilburt, JC, Konety, B, Williams, SB, Weight, CJ, Yu, JB, Kumar, AMS, Meropol, NJ. Perceptions of Barriers Towards Active Surveillance for Low-Risk Prostate Cancer: Results From a National Survey of Radiation Oncologists and Urologists. Ann. Surg. Oncol. 2018; : . PubMed PMID:30311161 .
  7. Kim, SP, Meropol, NJ, Gross, CP, Tilburt, JC, Konety, B, Yu, JB, Abouassaly, R, Weight, CJ, Williams, SB, Shah, ND. Physician attitudes about genetic testing for localized prostate cancer: A national survey of radiation oncologists and urologists. Urol. Oncol. 2018; 36 (11): 501.e15-501.e21. PubMed PMID:30190177 .
  8. Sausville, LN, Gangadhariah, MH, Chiusa, M, Mei, S, Wei, S, Zent, R, Luther, JM, Shuey, MM, Capdevila, JH, Falck, JR, Guengerich, FP, Williams, SM, Pozzi, A. The Cytochrome P450 Slow Metabolizers CYP2C9*2 and CYP2C9*3 Directly Regulate Tumorigenesis via Reduced Epoxyeicosatrienoic Acid Production. Cancer Res. 2018; 78 (17): 4865-4877. PubMed PMID:30012669 PubMed Central PMC6125168.
  9. Huusko, JM, Karjalainen, MK, Graham, BE, Zhang, G, Farrow, EG, Miller, NA, Jacobsson, B, Eidem, HR, Murray, JC, Bedell, B, Breheny, P, Brown, NW, Bødker, FL, Litterman, NK, Jiang, PP, Russell, L, Hinds, DA, Hu, Y, 23andMe Research Team, Rokas, A, Teramo, K, Christensen, K, Williams, SM, Rämet, M, Kingsmore, SF, Ryckman, KK, Hallman, M, Muglia, LJ. Whole exome sequencing reveals HSPA1L as a genetic risk factor for spontaneous preterm birth. PLoS Genet. 2018; 14 (7): e1007394. PubMed PMID:30001343 PubMed Central PMC6042692.
  10. Ndiaye Diallo, R, Gadji, M, Hennig, BJ, Guèye, MV, Gaye, A, Diop, JPD, Sylla Niang, M, Lopez Sall, P, Guèye, PM, Dem, A, Faye, O, Dieye, A, Cisse, A, Sembene, M, Ka, S, Diop, N, Williams, SM, Matovu, E, Ramesar, RS, Wonkam, A, Newport, M, Rotimi, C, Ramsay, M. Strengthening human genetics research in Africa: report of the 9th meeting of the African Society of Human Genetics in Dakar in May 2016. Glob Health Epidemiol Genom 2017; 2 : e10. PubMed PMID:29868221 PubMed Central PMC5870411.
Search PubMed