Bush, William S., PhD

Will Bush_crop

William S. Bush, PhD

Assistant Professor

wsb36@case.edu | 216.368.0957 | Wolstein Research Bldg. 2530

 

Education

Ph.D., 2008, Vanderbilt University
M.S., 2008, Vanderbilt University

Recent Publications

  1. Hart, NJ, Aramandla, R, Poffenberger, G, Fayolle, C, Thames, AH, Bautista, A, Spigelman, AF, Babon, JAB, DeNicola, ME, Dadi, PK, Bush, WS, Balamurugan, AN, Brissova, M, Dai, C, Prasad, N, Bottino, R, Jacobson, DA, Drumm, ML, Kent, SC, MacDonald, PE, Powers, AC. Cystic fibrosis-related diabetes is caused by islet loss and inflammation. JCI Insight 2018; 3 (8): . PubMed PMID:29669939 PubMed Central PMC5931120.
  2. Butkiewicz, M, Blue, E, Leung, F, Jian, X, Marcora, E, Renton, A, Kuzma, A, Wang, LS, Koboldt, D, Haines, JL, Bush, WS. Functional Annotation of genomic variants in studies of Late-Onset Alzheimer's Disease. Bioinformatics 2018; : . PubMed PMID:29590295 .
  3. Blue, EE, Bis, JC, Dorschner, MO, Tsuang, DW, Barral, SM, Beecham, G, Below, JE, Bush, WS, Butkiewicz, M, Cruchaga, C, DeStefano, A, Farrer, LA, Goate, A, Haines, J, Jaworski, J, Jun, G, Kunkle, B, Kuzma, A, Lee, JJ, Lunetta, KL, Ma, Y, Martin, E, Naj, A, Nato, AQ, Navas, P, Nguyen, H, Reitz, C, Reyes, D, Salerno, W, Schellenberg, GD, Seshadri, S, Sohi, H, Thornton, TA, Valadares, O, van Duijn, C, Vardarajan, BN, Wang, LS, Boerwinkle, E, Dupuis, J, Pericak-Vance, MA, Mayeux, R, Wijsman, EM, on behalf of the Alzheimer’s Disease Sequencing Project. Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project. Dement Geriatr Cogn Disord 2018; 45 (1-2): 1-17. PubMed PMID:29486463 .
  4. Sivley, RM, Dou, X, Meiler, J, Bush, WS, Capra, JA. Comprehensive Analysis of Constraint on the Spatial Distribution of Missense Variants in Human Protein Structures. Am. J. Hum. Genet. 2018; 102 (3): 415-426. PubMed PMID:29455857 .
  5. Gong, J, Nishimura, KK, Fernandez-Rhodes, L, Haessler, J, Bien, S, Graff, M, Lim, U, Lu, Y, Gross, M, Fornage, M, Yoneyama, S, Isasi, CR, Buzkova, P, Daviglus, M, Lin, DY, Tao, R, Goodloe, R, Bush, WS, Farber-Eger, E, Boston, J, Dilks, HH, Ehret, G, Gu, CC, Lewis, CE, Nguyen, KH, Cooper, R, Leppert, M, Irvin, MR, Bottinger, EP, Wilkens, LR, Haiman, CA, Park, L, Monroe, KR, Cheng, I, Stram, DO, Carlson, CS, Jackson, R, Kuller, L, Houston, D, Kooperberg, C, Buyske, S, Hindorff, LA, Crawford, DC, Loos, RJF, Le Marchand, L, Matise, TC, North, KE, Peters, U. Trans-ethnic analysis of metabochip data identifies two new loci associated with BMI. Int J Obes (Lond) 2018; 42 (3): 384-390. PubMed PMID:29381148 PubMed Central PMC5876082.
  6. Sivley, RM, Sheehan, JH, Kropski, JA, Cogan, J, Blackwell, TS, Phillips, JA, Bush, WS, Meiler, J, Capra, JA. Three-dimensional spatial analysis of missense variants in RTEL1 identifies pathogenic variants in patients with Familial Interstitial Pneumonia. BMC Bioinformatics 2018; 19 (1): 18. PubMed PMID:29361909 PubMed Central PMC5781290.
  7. Bush, WS, Crawford, DC, Briggs, F, Freedman, D, Sloan, C. INTEGRATING COMMUNITY-LEVEL DATA RESOURCES FOR PRECISION MEDICINE RESEARCH. Pac Symp Biocomput 2018; 23 : 618-622. PubMed PMID:29218920 .
  8. Beecham, GW, Bis, JC, Martin, ER, Choi, SH, DeStefano, AL, van Duijn, CM, Fornage, M, Gabriel, SB, Koboldt, DC, Larson, DE, Naj, AC, Psaty, BM, Salerno, W, Bush, WS, Foroud, TM, Wijsman, E, Farrer, LA, Goate, A, Haines, JL, Pericak-Vance, MA, Boerwinkle, E, Mayeux, R, Seshadri, S, Schellenberg, G. The Alzheimer's Disease Sequencing Project: Study design and sample selection. Neurol Genet 2017; 3 (5): e194. PubMed PMID:29184913 PubMed Central PMC5646177.
  9. Conti, DV, Wang, K, Sheng, X, Bensen, JT, Hazelett, DJ, Cook, MB, Ingles, SA, Kittles, RA, Strom, SS, Rybicki, BA, Nemesure, B, Isaacs, WB, Stanford, JL, Zheng, W, Sanderson, M, John, EM, Park, JY, Xu, J, Stevens, VL, Berndt, SI, Huff, CD, Wang, Z, Yeboah, ED, Tettey, Y, Biritwum, RB, Adjei, AA, Tay, E, Truelove, A, Niwa, S, Sellers, TA, Yamoah, K, Murphy, AB, Crawford, DC, Gapstur, SM, Bush, WS, Aldrich, MC, Cussenot, O, Petrovics, G, Cullen, J, Neslund-Dudas, C, Stern, MC, Jarai, ZK, Govindasami, K, Chokkalingam, AP, Hsing, AW, Goodman, PJ, Hoffmann, T, Drake, BF, Hu, JJ, Clark, PE, Van Den Eeden, SK, Blanchet, P, Fowke, JH, Casey, G, Hennis, AJM, Han, Y, Lubwama, A, Thompson, IM Jr, Leach, R, Easton, DF, Schumacher, F, Van den Berg, DJ, Gundell, SM, Stram, A, Wan, P, Xia, L, Pooler, LC, Mohler, JL, Fontham, ETH, Smith, GJ, Taylor, JA, Srivastava, S, Eeles, RA, Carpten, J, Kibel, AS, Multigner, L, Parent, ME, Menegaux, F, Cancel-Tassin, G, Klein, EA, Brureau, L, Stram, DO, Watya, S, Chanock, SJ, Witte, JS, Blot, WJ, Henderson, BE, Haiman, CA, PRACTICAL/ELLIPSE Consortium. Two Novel Susceptibility Loci for Prostate Cancer in Men of African Ancestry. J. Natl. Cancer Inst. 2017; 109 (8): . PubMed PMID:29117387 PubMed Central PMC5448553.
  10. Li, Y, Xiao, X, Han, Y, Gorlova, O, Qian, D, Leighl, N, Johansen, JS, Barnett, M, Chen, C, Goodman, G, Cox, A, Taylor, F, Woll, P, Wichmann, HE, Manz, J, Muley, T, Risch, A, Rosenberger, A, Arnold, SM, Haura, EB, Bolca, C, Holcatova, I, Janout, V, Kontic, M, Lissowska, J, Mukeria, A, Ognjanovic, S, Orlowski, TM, Scelo, G, Swiatkowska, B, Zaridze, D, Bakke, P, Skaug, V, Zienolddiny, S, Duell, EJ, Butler, LM, Houlston, R, Soler Artigas, M, Grankvist, K, Johansson, M, Shepherd, FA, Marcus, MW, Brunnström, H, Manjer, J, Melander, O, Muller, DC, Overvad, K, Trichopoulou, A, Tumino, R, Liu, G, Bojesen, SE, Wu, X, Marchand, LL, Albanes, D, Bickeböller, H, Aldrich, MC, Bush, WS, Tardon, A, Rennert, G, Teare, MD, Field, JK, Kiemeney, LA, Lazarus, P, Haugen, A, Lam, S, Schabath, MB, Andrew, AS, Bertazzi, PA, Pesatori, AC, Christiani, DC, Caporaso, N, Johansson, M, McKay, JD, Brennan, P, Hung, RJ, Amos, CI. Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population. Carcinogenesis 2018; 39 (3): 336-346. PubMed PMID:29059373 .
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